June 28, 2023

Psychedelics and Parasites: A Complex Relationship

Psychedelics and Parasites: A Complex Relationship

The relationship between psychedelics and parasites is a complex and understudied area. While some anecdotal reports suggest that certain psychedelic substances may aid in the elimination of parasites, scientific research in this field is limited. This article explores the available information on the connection between psychedelics and parasites, providing references where possible.

Anecdotal Reports of Parasite Elimination

Some users of traditional plant medicines, such as Ayahuasca, have reported the elimination of parasites following the consumption of these substances. Although these reports are anecdotal, they indicate that further research is warranted. One potential explanation is that the vomiting and diarrhea that can occur during an Ayahuasca ceremony may help to expel parasites from the body.

Reference: Jauregui, X., Clavo, Z. M., Jovel, E. M., & Pardo-de-Santayana, M. (2011). "Plantas con madre": plants that teach and guide in the shamanic initiation process in the East-Central Peruvian Amazon. Journal of Ethnopharmacology, 134(3), 739-752.

Antiparasitic Properties of Psychedelic Plant Compounds

Some plant-based psychedelic substances, such as Ibogaine (derived from the Tabernanthe iboga plant), have demonstrated antiparasitic properties in preclinical studies. It is possible that the consumption of such substances could contribute to the reduction of parasite load in the human body. However, more research is needed to understand the efficacy and safety of these compounds for parasite elimination.

Reference: Kontrimaviciute, V., Mathieu, O., Mathieu-Daude, J. C., Vainauskas, P., Casper, T., Baccino, E., ... & Gollotte, A. (2006). Distribution of ibogaine and noribogaine in a man following a poisoning involving root bark of the Tabernanthe iboga shrub. Journal of Analytical Toxicology, 30(7), 434-440.

The Gut-Brain Connection and Psychedelics

Emerging research on the gut-brain axis suggests that the health of our gut microbiome can significantly impact our mental well-being. Given that parasites can disrupt the balance of the gut microbiome, it is possible that psychedelic substances may indirectly affect parasite presence by influencing the gut-brain connection. Further research is needed to elucidate the exact mechanisms and implications of this relationship.

Reference: Sherwin, E., Sandhu, K. V., Dinan, T. G., & Cryan, J. F. (2016). May the Force Be With You: The Light and Dark Sides of the Microbiota-Gut-Brain Axis in Neuropsychiatry. CNS drugs, 30(11), 1019-1041.

While anecdotal reports and preliminary research suggest a potential link between psychedelics and parasite elimination, the current body of scientific evidence is limited. Further research is needed to understand the mechanisms underlying this relationship, as well as the safety and efficacy of psychedelic substances for parasite elimination. Additionally, the potential influence of psychedelics on the gut-brain axis could play a role in the complex relationship between psychedelics and parasites.